2-hydroxyphytanoyl-CoA lyase
2-Hydroxyphytanoyl-CoA lyase is a peroxisomal enzyme involved in the catabolism of phytanoic acid by α-oxidation. It requires thiamine diphosphate (ThDP) as cofactor.[1]
It is classified under EC number 4.1.
File:Alpha oxidation part III.svg
References
- ↑ Foulon V, Antonenkov V, Croes K, et al. (1999). “Purification, molecular cloning, and expression of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine pyrophosphate-dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids”. Proc. Natl. Acad. Sci. U.S.A. 96 (18): 10039–44. doi:10.1073/pnas.96.18.10039. PMC 17838. PMID 10468558.
External links
- 2-hydroxyphytanoyl-coenzyme+A+lyase at the US National Library of Medicine Medical Subject Headings (MeSH)
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