AFCAPS/TexCAPS Trial

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Click here to download slides for AFCAPS/TexCAPS.

Overview

Lovastatin 20-40 mg daily (in addition to low-saturated ad low-colesterol diet) reduced the incidence of first major acute cardiovascular event (MACE) during a follow-up of 5.2 years, in this study involving 5608 men and 997 women with average total cholesterol and LDL levels and low HDL levels^[1].

References

↑ Downs JR, Clearfield M, Weis S, Whitney E, Shapiro DR, Beere PA; et al. (1998). “Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study”. JAMA. 279 (20): 1615–22. PMID 9613910.

[pmid9613910-1] Downs JR, Clearfield M, Weis S, Whitney E, Shapiro DR, Beere PA; et al. (1998). “Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study”. JAMA. 279 (20): 1615–22. PMID 9613910.

[1]