Antistreptolysin O titer
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Antistreptolysin O titre (AS(L)O titre or AS(L)OT) – titre of (serum) antistreptolysin O antibodies; a blood test used to assist in the diagnosis of a streptococcal infection or indicate a past exposure to streptococci.
The ASOT helps direct the antimicrobial treatment and is used to assist in the diagnosis of scarlet fever, rheumatic fever and post infectious glomerulonephritis.
A positive test usually is >200 units/mL,[1] but normal ranges vary from laboratory to laboratory and by age.[2]
The false negatives rate is 20-30%.[1] If a false negative is suspected then an anti-DNase B titre should be sought. False positives can result from liver disease and tuberculosis.[1]
References
- ↑ 1.0 1.1 1.2 Antistreptococcal antibody titres. gpnotebook. URL: http://www.gpnotebook.co.uk/cache/-1630535637.htm. Accessed on: March 31, 2007.
- ↑ Danchin M, Carlin J, Devenish W, Nolan T, Carapetis J (2005). “New normal ranges of antistreptolysin O and antideoxyribonuclease B titres for Australian children”. J Paediatr Child Health. 41 (11): 583–6. PMID 16398843.
See also
External links
- Antistreptococcal antibody titres – GPnotebook.co.uk.
- Antistreptolysin O Titer – medterms.com.
- Antistreptolysin O Titer, Serum
- Streptococcal antibody tests – healthAtoZ.com
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