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Acromegaly epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

The prevalence of acromegaly is estimated to be 2.8 – 13.7 per 100.000 individuals worldwide. In the United States, the incidence of acromegaly is 0.11 per 100,000 indvidual. Acromegaly affects men and women equally.

Epidemiology and Demographics

Incidence

  • The incidence of acromegaly is approximately 0.2 – 1.1 per 100,000 individuals worldwide.[1][2][3]

Prevalence

  • The prevalence of acromegaly is approximately 2.8 – 13.7 per 100,000 individuals worldwide.[4][5]

Age

  • The incidence of acromegaly increases with age; the mean age at diagnosis of acromegaly is 40 years in males.
  • The mean age at diagnosis of acromegaly is 45 years in females.

Race

  • There is no racial predilection to acromegaly.

Gender

  • Acromegaly affects men and women equally.[6]

Developed Countries

  • In the United States, acromegaly is very rare. The incidence of acromegaly in the United States is 0.11 per 100,000 individual.
  • In Iceland, the incidence of acromegaly is 0.7 per 100,000 individual.[7]

References

  1. ↑ Bengtsson BA, Edén S, Ernest I, Odén A, Sjögren B (1988). “Epidemiology and long-term survival in acromegaly. A study of 166 cases diagnosed between 1955 and 1984”. Acta Med Scand. 223 (4): 327–35. PMID 3369313.
  2. ↑ Lavrentaki A, Paluzzi A, Wass JA, Karavitaki N (2017). “Epidemiology of acromegaly: review of population studies”. Pituitary. 20 (1): 4–9. doi:10.1007/s11102-016-0754-x. PMC 5334410. PMID 27743174.
  3. ↑ Dal J, Feldt-Rasmussen U, Andersen M, Kristensen LØ, Laurberg P, Pedersen L; et al. (2016). “Acromegaly incidence, prevalence, complications and long-term prognosis: a nationwide cohort study”. Eur J Endocrinol. 175 (3): 181–90. doi:10.1530/EJE-16-0117. PMID 27280374.
  4. ↑ Bengtsson BA, Edén S, Ernest I, Odén A, Sjögren B (1988). “Epidemiology and long-term survival in acromegaly. A study of 166 cases diagnosed between 1955 and 1984”. Acta Med Scand. 223 (4): 327–35. PMID 3369313.
  5. ↑ Holdaway IM, Rajasoorya C (1999). “Epidemiology of acromegaly”. Pituitary. 2 (1): 29–41. PMID 11081170.
  6. ↑ Ezzat S, Forster MJ, Berchtold P, Redelmeier DA, Boerlin V, Harris AG (1994). “Acromegaly. Clinical and biochemical features in 500 patients”. Medicine (Baltimore). 73 (5): 233–40. PMID 7934807.
  7. ↑ Hoskuldsdottir GT, Fjalldal SB, Sigurjonsdottir HA (2015). “The incidence and prevalence of acromegaly, a nationwide study from 1955 through 2013”. Pituitary. 18 (6): 803–7. doi:10.1007/s11102-015-0655-4. PMID 25893613.

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