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Acute chest syndrome overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Acute Chest Syndrome is a vaso-occlusive crisis of the pulmonary vasculature commonly seen in patients with Sickle Cell Anemia. Acute Chest Syndrome is often initiated by a lung infection and the resulting inflammation and loss of oxygen tension leads to sickling of red cells and further vaso-occlusion. Acute Chest Syndrome is one of the most common causes of death for Sickle Cell patients.[1]

References

  1. Kumar, Abbas, Fausto. Robbins and Cotran: The Pathologic Basis of Disease, Page 631


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