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Acute myelomonocytic leukemia

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

Acute myelomonocytic leukemia (AMMoL) is a form of acute myeloid leukemia which involves a proliferation of CFU-GM myeloblasts and monoblasts.

It is classified under “M4” in the French-American-British classification (FAB).[1]

It is classified under “AML, not otherwise classified” in the WHO classification.[2]

Translocations have been observed.[3]

Progression from myelodysplastic syndrome has been reported.[4]

See also

References

  1. “Acute Myeloid Leukemia – Signs and Symptoms”.
  2. “eMedicine – Acute Myelogenous Leukemia : Article by Karen Seiter”.
  3. Yamamoto K, Nagata K, Tsurukubo Y; et al. (2002). “Translocation (8;12)(q13;p13) during disease progression in acute myelomonocytic leukemia with t(11;19)(q23;p13.1)”. Cancer Genet. Cytogenet. 137 (1): 64–7. PMID 12377416.
  4. Zhang L, Alsabeh R, Mecucci C; et al. (2007). “Rare t(1;11)(q23;p15) in therapy-related myelodysplastic syndrome evolving into acute myelomonocytic leukemia: a case report and review of the literature”. Cancer Genet. Cytogenet. 178 (1): 42–8. doi:10.1016/j.cancergencyto.2007.06.012. PMID 17889707.



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