Acute uric acid nephropathy medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Treatment is focused on preventing deposition of uric acid within the urinary system by increasing urine volume with potent diuretics such as furosemide. The urine must also be alkalinized to pH > 7 using sodium bicarbonate and/or acetazolamide to increase uric acid solubility.

Dialysis (preferably hemodialysis) is started if the above measures fail.

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