Acute uric acid nephropathy pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Acute uric acid nephropathy is caused by deposition of uric acid crystals within the kidney interstitium and tubules, leading to partial or complete obstruction of collecting ducts, renal pelvis, or ureter. This obstruction is usually bilateral, and patients follow the clinical course of acute renal failure.

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