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Addison's disease CT

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

There are no specific CT findings associated with Addisons’s disease. However, the ct may show findings of bilateral adrenal remnants and calcifications suggesting autoimmune adrenalitis or tuberculosis adrenalitis.

CT Scan

Abdominal CT findings in Addison’s disease may include:[1]

  • Small adrenal remnants bilaterally suggestive of autoimmune adrenalitis, idiopathic atrophy, or long-term tuberculosis infection.
  • Dense calcification in one or both adrenal beds without evidence of normal glandular remnants – in TB.
  • Enlarged nonhomogeneous glands of normal contour – in Histoplasmosis.
  • Atrophic adrenal glands – in idiopathic autoimmune Addison’s disease.
Bilateral adrenal diffuse enlargement (larger and mass like on the left side) showing calcfications. Source: Case courtesy of Dr Dalia Ibrahim, Radiopaedia.org, rID: 49318

References

  1. Doppman JL, Gill JR, Nienhuis AW, Earll JM, Long JA (1982). “CT findings in Addison’s disease”. J Comput Assist Tomogr. 6 (4): 757–61. PMID 7119194.

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