Addison's disease epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

The prevalence of Addison’s disease in the human population is estimated to be roughly 4-12 persons per 100,000 persons. The incidence of Addison’s disease is approximately 0.6 per 100,000 individuals worldwide. Addison’s disease can affect any age range. Addison’s disease occurs more frequently in females as compared to males with a ratio of 12.3 to 1.

The prevalence of Addison’s disease in the human population is sometimes estimated at roughly 4-12 people per 100,000 persons.

The incidence Addison’s disease is approximately 0.6 per 100,000 individuals worldwide.

• Addison disease can affect any age range.
• Addison’s disease typically presents in adults between 30 and 50 years of age as most are often diagnosed with autoimmune-associated diseases.^[1]

Addison’s disease occur more frequently in females as compared to males with a ratio of 12.3 to 1. ^[2]

There is no racial predilection to Addison’s disease.

Addison’s disease may be more common in areas where systemic fungal infections such as histoplasmosis can cause destruction of the adrenal cortex by disseminated infection or secondary to antifungal medications.

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