Adrenocortical carcinoma epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Ahmad Al Maradni, M.D. [3] Mohammed Abdelwahed M.D[4]

The incidence of adrenocortical carcinoma is believed to be 0.72 per million cases per year leading to 0.2% of all cancer deaths in the United States and 0.2 to 0.3 per million children per year worldwide but valid data is lacking. A bimodal distribution is observed, the first one in pediatrics and the second one in the fifth to the sixth decade with a predilection for the female gender.

• The incidence of adrenocortical carcinoma is 7.2 cases per 100,000 individuals per year leading to 0.2% of all cancer deaths in the United States and 3 cases per 100,000 children per year worldwide but valid data is lacking.^[1]

• A bimodal distribution was observed, the first one in pediatrics and the second one in the fifth to the sixth decade.^[2]

• There is a predilection for the female gender.^[3]
• Girls are also more commonly affected than boys with a ratio of 1.6:1.^[4]

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