Amanullinic acid
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Amanullinic acid is a cyclic nonribosomal peptide. It is an amatoxin, all of which are found in several members of the Amanita genus of mushrooms. The oral LD50 of amanullinic acid is approximately 20 mg/kg in mice,[1] however it is reported to be non-toxic in humans.
Toxicology
Like other amatoxins, amanullinic acid is an inhibitor of RNA polymerase II.
See also
References
- ↑ T. Wieland and Faulstich H. (1978). “Amatoxins, Phallotoxins, Phallolysin, and Antamanide: the Biologically Active Components of Poisonous Amanita Mushrooms”. CRC Critical Reviews in Biochemistry. 5: 185. doi:10.3109/10409237809149870.
External links
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