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Aminoadipate-semialdehyde dehydrogenase

Aminoadipate-semialdehyde dehydrogenase is a protein that in humans is encoded by the AASDH gene. [1]

Function

This gene encodes a member of the non-ribosome peptide syntesase (NRPS) enzyme family. The encoded protein contains an AMP-binding domain, PP-binding (phosphopantetheine, or pantetheine 4’phosphate-binding) domain and the Pyrrolo-quinoline quinon (PQQ) binding domain. The protein is expressed in several adult tissues.

References

Further reading

  • Wang L, Jil C, Xu Y, Xu J, Dai J, Wu Q, Wu M, Zou X, Sun L, Gu S, Xie Y, Mao Y (2005). “Cloning and characterization of a novel human homolog* of mouse U26, a putative PQQ-dependent AAS dehydrogenase”. Mol. Biol. Rep. 32 (1): 47–53. PMID 15865210.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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