Amyotrophic lateral sclerosis risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Common risk factors in the development and progression of amyotrophic lateral sclerosis largely remain unknown. Other common risk factors associated include: Age, Smoking, oxidative stress.

• Common risk factors in the development of [Amyotrophic lateral sclerosis] include:
  • Smoking
    • Cigarette smoke might be considered an established risk factor for Sporadic Amyotrophic lateral sclerosis (level A rating, 3 class II studies, 1 class III study).^[1]
  • Chemical exposure
    • ALS has shown an association with exposure to agricultural chemicals such as pesticides, fertilizers, herbicides, insecticides, and formaldehyde.^[2]
    • Among all the heavy metals that might be associated with ALS, lead exposure seems to be studied the most possibly due to the ALS-like symptoms experienced by people exposed to high concentrations of lead.^[3]
  • Radiation
  • Diet
    • High level of glutamate and fat can have adverse effects on ALS patients while Omega 3 fatty acids, Vitamin E, and fiber can have defensive impact.^[4][5]
  • Genetic causes^[6]

Template:WH Template:WS