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Anal cancer medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]

Overview

The predominant therapy for anal cancer is chemotherapy and radiation.[1]

Medical therapy

Minimal invasive methods such as infrared coagulation is indicated for localized anal cancer.[2] Chemotherapy and radiation are the first-line therapy for metastatic disease.[3]

Localized anal cancer is treated with minimal invasive treatment as infrared coagulation.

Metastatic anal cancer is treated with chemotherapy (fluorouracil (5-FU) and cisplatin) concurrent with radiation.

References

  1. National Cancer Institute. Physician Data Query Database 2015.http://www.cancer.gov/types/anal/hp/anal-treatment-pdq#section/_36
  2. Goldstone, SE, Kawalek, AZ, Huyett, JW “Infrared Photocoagulator: A useful tool for treating anal squamous intraepithelial lesions”. 2005. Diseases of the Colon & Rectum 58(5), 1042–1053.
  3. National Comprehensive Cancer Network. “NCCN Clinical Practice Guidelines in Oncology: Anal Carcinoma. V 1.2013” (PDF).

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