Analgesic nephropathy physical examination
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]
Overview
In physical examination of patients with analgesic nephropathy checking for the followings should be considered: headache, upper gastrointestinal disease (such as peptic ulcer), anemia, urinary tract infections, and hypertension.
Physical Examination
In physical examination of patients with analgesic nephropathy checking for the followings should be considered:[1][2]
- Headache
- Upper gastrointestinal disease (such as peptic ulcer)
- Anemia (60%)
- Urinary tract infections (15-60%)
- Hypertension (15-70%)
- Microscopic hematuria (35%)
- Significant proteinuria (greater than 0.3 gr daily) (40%)
- Transitional cell tumours of the urothelium (in abuse of analgesics containing phenacetin)
- Varying degrees of renal failure (over 85%)
- Clinical gout (5%)
- Passage of papillae
- Flank or abdominal pain
References
- ↑ Nanra RS (1980). “Clinical and pathological aspects of analgesic nephropathy”. Br J Clin Pharmacol. 10 Suppl 2: 359S–368S. doi:10.1111/j.1365-2125.1980.tb01824.x. PMC 1430193. PMID 7002190.
- ↑ Nanra RS, Stuart-Taylor J, de Leon AH, White KH (1978). “Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia”. Kidney Int. 13 (1): 79–92. doi:10.1038/ki.1978.11. PMID 362034.
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