Phenazone
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Phenazone, or phenazon, is an analgesic. It is formed by reducing diortho-dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochloric acid to 150 C. It crystallizes in needles which melt at 156 C. Potassium permanganate oxidizes it to pyridazine tetracarboxylic acid.
Synonyms
Analgesine, Antipyrine, Diméthyloxyquinazine, Oxydiméthylquinazine, Oxydiméthylquinizine, Pyrazoline
See also
Chimic Class
- Pyrazole
- Pyrazolinone
Pharmacology
Adverse effects
- Allergy to pyrazolones
- Nausea
- Agranulocytosis
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