Antithrombin III deficiency natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

In renal failure, especially nephrotic syndrome, antithrombin is lost in the urine, leading to a higher activity of Factor II and Factor X and in increased tendency to thrombosis.

Blood clots can cause death, especially if they are in the lungs.

Most patients have a good outcome if they stay on anticoagulant medications.

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