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Aphthous ulcer historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: José Eduardo Riceto Loyola Junior, M.D.[2]

Overview

  • The term aphthae was first used by Hippocrates at between 460-370 B.C., in relation to disorders of the mouth.

Historical perspective

  • The term aphthae was first used by Hippocrates at between 460-370 B.C., in relation to disorders of the mouth.[1]
  • In 1898, the first clinical description of the aphthous stomatitis was reported by Von Mikulicz and Kumme as a Mikuliez aphthea
  • In 1911, stomatitis aphthae recurrens cicatricicans was first described by Sutton.
  • In 1961, stomatitis aphthae recurrens herpetiformis was first described by Cooke.[2]

References

  1. Ship, Jonathan A. “Recurrent aphthous stomatitis: an update.” Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 81.2 (1996): 141-147.
  2. Rogers RS (1977). “Recurrent aphthous stomatitis: clinical characteristics and evidence for an immunopathogenesis”. J Invest Dermatol. 69 (6): 499–509. doi:10.1111/1523-1747.ep12687958. PMID 336797.

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