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Asperger syndrome future or investigational therapies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]

Overview

There have been some experimental therapy and suggestions such as oxytocin and treatment with stem cells in patients with Asperger Syndrome (AS).[1]

Future or Investigational Therapies

Experimental therapy for Asperger Syndrome (AS) include:[1]

Oxytocin

  • Contributions to repetitive behaviors and social deficiencies in Asperger Syndrome (AS) by oxytocin have suggested oxytocin as an experimental therapy in autism spectrum disorder (ASD) and Asperger Syndrome (AS).[2]
  • In patients with AS and ASD, the preliminary manipulation of systemic oxytocin levels have suggested a positive correlation in social awareness, social recognition and peer affiliation.[3]  

Stem cells  

  • Treatment of AS and ASD with stem cells is in the early stages.[1]

References

  1. 1.0 1.1 1.2 Tarazi FI, Sahli ZT, Pleskow J, Mousa SA (2015). “Asperger’s syndrome: diagnosis, comorbidity and therapy”. Expert Rev Neurother. 15 (3): 281–93. doi:10.1586/14737175.2015.1009898. PMID 25655905.
  2. Hollander E, Novotny S, Hanratty M, Yaffe R, DeCaria CM, Aronowitz BR; et al. (2003). “Oxytocin infusion reduces repetitive behaviors in adults with autistic and Asperger’s disorders”. Neuropsychopharmacology. 28 (1): 193–8. doi:10.1038/sj.npp.1300021. PMID 12496956.
  3. Andari E, Duhamel JR, Zalla T, Herbrecht E, Leboyer M, Sirigu A (2010). “Promoting social behavior with oxytocin in high-functioning autism spectrum disorders”. Proc Natl Acad Sci U S A. 107 (9): 4389–94. doi:10.1073/pnas.0910249107. PMC 2840168. PMID 20160081.

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