Aspergillosis risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Haytham Allaham, M.D. [2]; Serge Korjian M.D.

Immunocompromised status and history of prior lung disease are the most important risk factors in the development of aspergillosis. Other risk factors include history of asthma, burn or surgical site wounds, and exposure to healthcare settings or construction sites.

Immunocompromised status and history of prior lung disease are the most important risk factors in the development of aspergillosis.
Risk factors include:

• Asthma
• Burn wound
• History of lung disease (e.g. COPD, interstitial lung disease, bronchiectasis)
• Chemotherapy
• Cystic fibrosis
• Diabetes mellitus
• Drug intake (immunosuppressive or immunomodulating therapy)
• Exposure to construction sites
• Exposure to healthcare settings
• Granulocytopenia
• HIV/AIDS
• Malignancy
• Radiotherapy
• Solid organ transplantation
• Stem cell transplantation
• Surgical site wound
• Tuberculosis

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