Autism risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

Common risk factors in the development of autism include male gender, advanced maternal and paternal age, low birth weight, hypoxia during childbirth, and family history schizophrenia.

Risk Factors

Common risk factors in the development autism include:

Male gender: boys are at higher risk for autism than girls.^[1]
Prenatal and perinatal risk factors:
- Advanced maternal age
- Advanced paternal age
- Low birth weight
- Gestation duration
- Hypoxia during childbirth^[2]
Family history schizophrenia^[3]

References

↑ Newschaffer CJ, Croen LA, Daniels J; et al. (2007). “The epidemiology of autism spectrum disorders”. Annu Rev Public Health. 28: 235–58. doi:10.1146/annurev.publhealth.28.021406.144007. PMID 17367287.
↑ Kolevzon A, Gross R, Reichenberg A (2007). “Prenatal and perinatal risk factors for autism”. Arch Pediatr Adolesc Med. 161 (4): 326–33. doi:10.1001/archpedi.161.4.326. PMID 17404128.
↑ Daniels JL, Forssen U, Hultman CM; et al. (2008). “Parental psychiatric disorders associated with autism spectrum disorders in the offspring”. Pediatrics. 121 (5): e1357–62. doi:10.1542/peds.2007-2296. PMID 18450879. Lay summary – UNC News (2008-05-05).

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[Newschaffer-1] Newschaffer CJ, Croen LA, Daniels J; et al. (2007). “The epidemiology of autism spectrum disorders”. Annu Rev Public Health. 28: 235–58. doi:10.1146/annurev.publhealth.28.021406.144007. PMID 17367287.

[Kolevzon-2] Kolevzon A, Gross R, Reichenberg A (2007). “Prenatal and perinatal risk factors for autism”. Arch Pediatr Adolesc Med. 161 (4): 326–33. doi:10.1001/archpedi.161.4.326. PMID 17404128.

[3] Daniels JL, Forssen U, Hultman CM; et al. (2008). “Parental psychiatric disorders associated with autism spectrum disorders in the offspring”. Pediatrics. 121 (5): e1357–62. doi:10.1542/peds.2007-2296. PMID 18450879. Lay summary – UNC News (2008-05-05).

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