B-cell lymphoma physical examination

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Adnan Ezici, M.D[2]

Common physical examination findings of B cell lymphomas include peripheral lymphadenopathy, central lymphadenopathy, fever, pruritus, pallor, petechiae, jaundice, chest tenderness, abdominal distension, abdominal tenderness, and hepatosplenomegaly.

The following physical examination findings may be present among patients with B cell lymphomas:^{[1][2][3][4][5]}

• Appearance of the Patients with B cell lymphomas depends on the stage of disease. Patients may present with cachexia in late disease stage.

• Fever
• Tachypnea
• Asymmetric pulse

• Skin examination of patients with B cell lymphomas include:
  • Pallor
  • Pruritus
  • Petechiae
  • Jaundice

• Abnormalities of the head/hair may include:
  • Icteric sclera
  • Nystagmus
• Patients may develop superior vena cava syndrome, which may present with:
  • Swelling of the face
  • Facial flushing/redness face or cheeks
  • Facial tenderness
  • Drooping eyelid
  • Swelling around the eye

• Cervical lymphadenopathy

• Thoracic masses suggestive of central lymphadenopathy
• Chest tenderness
• Pleural effusion may develop, which has signs and symptoms such as:
  • Wheezing
  • Decreased breath sounds
  • Asymmetric chest expansion
  • Hyperresonance lungs on chest auscultation

• Cardiovascular examination of patients with B cell lymphomas is usually normal.

• Abdominal examination of patients with B cell lymphomas include:
  • Abdominal distension
  • Abdominal tenderness
  • Hepatosplenomegaly
  • Abdominal masses suggestive of central lymphadenopathy

• Back examination of patients with B cell lymphomas is usually normal.

• Genitourinary examination of patients with B cell lymphomas is usually normal.

• Neuromuscular examination of patients with B cell lymphomas is usually normal.

• Peripheral lymphadenopathy
• Joint pain
• Edema
• Bone fractures

• Seizures

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