B-cell lymphoma risk factors
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Adnan Ezici, M.D[2]
Overview
Common risk factors in the development of B-cell lymphoma include family history, infections, obesity, drugs, environmental factors, genetic mutations, immunodeficiency states, and autoimmune diseases.
Risk Factors
Common Risk Factors
- Common risk factors in the development of [disease name] include:[1][2][3][4]
- First degree family history of non-Hodgkin lymphoma
- Infections such as Epstein Barr virus (EBV), HTLV-1, HHV8, Hepatitis C virus, Helicobacter pylori, and Coxiella burnetii
- Obesity (BMI≥30 kg/m2) in young patients
- Drugs such as phenytoin, digoxin, and TNF-a antagonist
- Environmental factors such as pesticides, solvents, organic chemicals, radiation exposure, etc.
- Genetic mutations
- Immunodeficiency states such as severe combined immunodeficiency, Wiskott-Aldrich syndrome, AIDS, and immunosuppressive therapy
- Autoimmune diseases such as rheumatoid arthritis, Sjögren’s syndrome, celiac disease, and Hashimoto’s thyroiditis
References
- ↑ Küppers R (April 2005). “Mechanisms of B-cell lymphoma pathogenesis”. Nat Rev Cancer. 5 (4): 251–62. doi:10.1038/nrc1589. PMID 15803153.
- ↑ Sapkota S, Shaikh H. PMID 32644754 Check
|pmid=value (help). Missing or empty|title=(help) - ↑ Jamil A, Mukkamalla S. PMID 32809661 Check
|pmid=value (help). Vancouver style error: initials (help); Missing or empty|title=(help) - ↑ Flowers CR, Skibola CF (January 2016). “Identifying risk factors for B-cell lymphoma”. Blood. 127 (1): 10–1. doi:10.1182/blood-2015-11-677203. PMC 4705601. PMID 26744436.
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