Barrett's esophagus laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2] Amresh Kumar MD [3]

Laboratory findings consistent with diagnosis of Barrett’s esophagus is the presence of acidic reflux in the esophagus through the ambulatory reflux monitoring.

The laboratory findings for Barrett’s esophagus are as follows:^[1]

• Test for H. Pylori infection should be done
• Changes often arise secondary to Helicobacter pylori infection^[2]

• Ambulatory reflux monitoring is recommended by the American College of Gastroenterology (ACG) as the only laboratory test to determine the presence of acidic reflux in the esophagus.^[3]
• Indications of ambulatory reflux monitoring include the following:^[4]
  • GERD diagnosis if it is not confirmed
  • Determine the time of reflux occurrence
  • Refractory GERD symptoms
  • Preoperative for non-erosive disease
• Ambulatory reflux monitoring is performed in either two ways which include:
  • Telemetry capsule (48 hours monitoring)
  • Transnasal catheter (24 hours monitoring)

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