Bladder cancer laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Steven C. Campbell, M.D., Ph.D. Associate Editor(s)-in-Chief: Farima Kahe M.D. [2], Shanshan Cen, M.D. [3]

Overview

Laboratory findings consistent with the diagnosis of bladder cancer include blood in the urine and abnormal cells in urine cytology. [Tumor marker]] tests include ladder tumour–associated antigen (BTA), uclear matrix proteins (NMP) and mucin and carcinoembryonic antigen (CEA).

Laboratory Findings

Laboratory findings consistent with the diagnosis of bladder cancer include:^[1]^[2]^[3]
Complete blood count

Low red blood cell count
Elevated alkaline phosphatase

Urinalysis

Hematuria

Urine cytology

Abnormal cells in the urine

Tumor marker tests

Bladder tumour–associated antigen (BTA)
Nuclear matrix proteins (NMP)
Mucin and carcinoembryonic antigen (CEA)

References

↑ Shariat SF, Karam JA, Lotan Y, Karakiewizc PI (2008). “Critical evaluation of urinary markers for bladder cancer detection and monitoring”. Rev Urol. 10 (2): 120–35. PMC 2483317. PMID 18660854.
↑ Villicana P, Whiting B, Goodison S, Rosser CJ (June 2009). “Urine-based assays for the detection of bladder cancer”. Biomark Med. 3 (3): 265. doi:10.2217/bmm.09.23. PMC 2819730. PMID 20161673.
↑ Grossfeld GD, Litwin MS, Wolf JS, Hricak H, Shuler CL, Agerter DC, Carroll PR (April 2001). “Evaluation of asymptomatic microscopic hematuria in adults: the American Urological Association best practice policy–part I: definition, detection, prevalence, and etiology”. Urology. 57 (4): 599–603. PMID 11306356.

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[pmid18660854-1] Shariat SF, Karam JA, Lotan Y, Karakiewizc PI (2008). “Critical evaluation of urinary markers for bladder cancer detection and monitoring”. Rev Urol. 10 (2): 120–35. PMC 2483317. PMID 18660854.

[pmid20161673-2] Villicana P, Whiting B, Goodison S, Rosser CJ (June 2009). “Urine-based assays for the detection of bladder cancer”. Biomark Med. 3 (3): 265. doi:10.2217/bmm.09.23. PMC 2819730. PMID 20161673.

[pmid11306356-3] Grossfeld GD, Litwin MS, Wolf JS, Hricak H, Shuler CL, Agerter DC, Carroll PR (April 2001). “Evaluation of asymptomatic microscopic hematuria in adults: the American Urological Association best practice policy–part I: definition, detection, prevalence, and etiology”. Urology. 57 (4): 599–603. PMID 11306356.

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