Buerger's disease causes
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
Buerger’s disease may be caused by tobacco smoking, rickettsial infection, or autoimmune phenomena.
Causes
Buerger’s disease may be caused by:
- Tobacco smoking
- Rickettsiae
- Autoimmune phenomenon
Genetic Causes
- Buerger disease may be caused by a mutation in DRBl*0405, DQAl *03, DQBl*0401, DPBl*0501, HLA-A54, HLA-A9,and HLA-B54 genes.
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | Smoking |
| Gastroenterologic | No underlying causes |
| Genetic | DRBl*0405, DQAl *03, DQBl*0401, DPBl*0501, HLA-A54, HLA-A9,and HLA-B54 |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | Rickettsial infection |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | Autoimmune with presence of anti-endothelial cell antibody and anti-cardiolipin antibodies |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in Alphabetical Order
- Autoimmune with presence of anti-endothelial cell antibody and anti-cardiolipin antibodies
- DRBl*0405, DQAl *03, DQBl*0401, DPBl*0501
- HLA-A54, HLA-A9,and HLA-B54
- Rickettsial infection
- Smoking
References
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