CAF regimen

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords: CAF; CAFFI; CAF Regimen; CDF; CTX/DOX/5-FU; Cyclophosphamide-Adriamycin-Fluorouracil Regimen; Cyclophosphamide/Doxorubicin/Fluorouracil; FAC

Overview

CAF regimen refers to a chemotherapy regimen consisting of cyclophosphamide, doxorubicin hdrochloride (Adriamycin), and fluorouracil, which may be used in the adjuvant setting for the treatment of nonmetastatic breast cancer or alone for the treatment of metastatic breast cancer.^[1]^[2]

Regimen

CCyclophosphamide

ADoxorubicin (Adriamycin)

FFluorouracil

Indications

Nonmetastatic breast cancer^[3]

References

↑ “NCI Thesaurus”.
↑ “R-CHOP – National Cancer Institute”.
↑ Khaloozadeh H, Yazdanbakhsh P, Homaei-shandiz F (2008). “The optimal dose of CAF regimen in adjuvant chemotherapy for breast cancer patients at stage IIB”. Math Biosci. 213 (2): 151–8. doi:10.1016/j.mbs.2008.04.003. PMID 18533195.

[1] “NCI Thesaurus”.

[2] “R-CHOP – National Cancer Institute”.

[pmid18533195-3] Khaloozadeh H, Yazdanbakhsh P, Homaei-shandiz F (2008). “The optimal dose of CAF regimen in adjuvant chemotherapy for breast cancer patients at stage IIB”. Math Biosci. 213 (2): 151–8. doi:10.1016/j.mbs.2008.04.003. PMID 18533195.

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