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Cardiac amyloidosis classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]

Overview

Cardiac amyloidosis can be classified based on the type of amyloid that infiltrates the heart. The types of amyloid that commonly deposit in the heart are immunoglobulin light chain (AL) and transthyretin (ATTR). These two types of amyloid can result in cardiac AL amyloidosis and cardiac transthyretin amyloidosis.

Classification

  • Cardiac amyloidosis can be classified based on the type of amyloid that infiltrates the heart.[1][2]
  • The types of amyloid that commonly deposit in the heart are immunoglobulin light chain (AL) transthyretin (ATTR).
  • Based on the above mentioned information, we can classify cardiac amyloidosis into:
  • Cardiac AL amyloidosis
  • Cardiac transthyretin amyloidosis

References

  1. Martinez-Naharro A, Hawkins PN, Fontana M (April 2018). “Cardiac amyloidosis”. Clin Med (Lond). 18 (Suppl 2): s30–s35. doi:10.7861/clinmedicine.18-2-s30. PMC 6334035. PMID 29700090.
  2. Quarta CC, Kruger JL, Falk RH (September 2012). “Cardiac amyloidosis”. Circulation. 126 (12): e178–82. doi:10.1161/CIRCULATIONAHA.111.069195. PMID 22988049.

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