Cardiotoxicity

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor in Chief: Cafer Zorkun, M.D., Ph.D. [2]

Cardiotoxicity is the occurrence of heart muscle damage. The heart becomes weaker and is not as efficient in pumping and therefore circulating blood. Cardiotoxicity may be caused by chemotherapy treatment, complications from anorexia nervosa, drugs or chemical toxins.

• Congestive heart failure

• Coronary thrombosis
• Arrhythmias
• Myocardial infarction
• Coronary vasoconstriction

• Epirubicin

• Congestive heart failure
• Cardiomyopathy

• Daunorubicin liposome

• Pericardial effusion, pericardial tamponade, ventricular extrasystoles, cardiac arrest, sinus tachycardia, atrial fibrillation, pulmonary hypertension, myocardial infarction, supraventricular tachycardia, and angina pectoris.

• Arrhythmias
• Dilated cardiomyopathy
• Congestive heart failure

• Myocardial ischemia
• Myocardial infarction
• Arrhythmias
• Eosinophilic myocarditis

• Electrocardiographic changes
• Arrhythmias
• Sudden cardiac death

• Mononuclear and histiocyte infiltration
• Electrocardiographic abnormalities

• Left-sided valvular lesions
• Fibrotic endocardial lesions
• Fibrotic pericardial lesions
• Restriction
• Pericardial constriction

• Arrhythmias
• Cardiac dysfunction

• Arrhythmias
• Cardiac dilatation with myofibrillar degeneration

• Electrocardiographic changes
• Arrhythmias
• Cardiomegaly

• Electrocardiographic changes
• Arrhythmias
• Congestive heart failure

• Arrhythmias
• Transient biventricular dysfunction

• Pericardial effusion in chronic exposure
• Edema PCBs may interfere with tissue permeability or cardiac function or both. ^[1]

• Bradycardia

• Myocarditis
• Myopericarditis
• Pericardial effusion
• Cardiac tamponade
• Congestive heart failure
• Supraventricular arrhythmias
• Ventricular arrhythmias

• Heart failure

• Chemocare.com: [3]

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