Cellulitis cost-effectiveness of therapy

The use of prophylactic antibiotic therapy to prevent the recurrence of cellulitis was shown to be cost-effective. Low dose penicillin serves to prevent future attacks and offers no significant increase in cost. ^[1]

A study done in a pediatric population comparing intravenous antibiotic treatment at home versus in the hospital setting showed the former as the more effective and less costly option. ^{[2] [3]}

With regard to diagnostic modalities, blood cultures have been shown to be of low yield, with minimal impact on clinical management, thereby not cost-effective for most patients. ^[4]

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