Cervical cancer primary prevention

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]

Most effective and cost efficient primary prevention available for cervical cancer is vaccination against high risk strains of human papilloma virus, which are HPV 16 and 18 and is given to adoloscent and young women ideally before the sexual debut.

Primary prevention method for cervical cancer is vaccination against HPV types 16 and 18, there are two type of FDA approved vaccines available in the market. These vaccines are most effective when it’s given to women age 9 to 26 and young male population through age 21 according to CDC recommendation. ^[1]

• HPV vaccine also is recommended for following target population:
  • Young homosexual or bisexual men who have sex with men through age 26
  • HIV infected young adult who have weakened immune system through age 26
  • Young adults who are transgender through age 26

• The trade name of the available FDA approved vaccines include: ^[2]
  • Gardasil, quadrivalent vaccine, composed of HPV 6, 11, 16 and 18.
  • Cervarix, bivalent vaccine, composed of HPV 16 and 18.

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