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Cervicitis natural history

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Prince Tano Djan, BSc, MBChB [2]

Overview

If left untreated, cervicitis may progress to PID with associated infectility especially in chronic cervicitis.[1][2] Untreated active HSV infections in the perinatal and neonatal period may lead to neonatal morbidity. Complications that can develop as a result of infectious cervicitis include:[3][1][4][5][6][7] pelvic inflammatory disease, infertility, chronic pelvic pain, ectopic pregnancy, spontaneous abortion, premature rupture of membranes and preterm delivery

Natural History

If left untreated, cervicitis may progress to PID with associated infectility especially in chronic cervicitis.[1][2] Untreated active HSV infections in the perinatal and neonatal period may lead to neonatal morbidity.

Complications

Complications that can develop as a result of infectious cervicitis are:[3][1][4][5][6][7]

Prognosis

References

  1. 1.0 1.1 1.2 1.3 Holló P, Jókai H, Herszényi K, Kárpáti S (2015). “[Genitourethral infections caused by D-K serotypes of Chlamydia trachomatis]”. Orv Hetil. 156 (1): 19–23. doi:10.1556/OH.2015.30078. PMID 25544050.
  2. 2.0 2.1 Soper DE (2010). “Pelvic inflammatory disease”. Obstet Gynecol. 116 (2 Pt 1): 419–28. doi:10.1097/AOG.0b013e3181e92c54. PMID 20664404.
  3. 3.0 3.1 Majeroni BA (1994). “Chlamydial cervicitis: complications and new treatment options”. Am Fam Physician. 49 (8): 1825–9, 1832. PMID 8203320.
  4. 4.0 4.1 Hill MG, Menon S, Smith S, Zhang H, Tong X, Browne PC (2015). “Screening for Chlamydia and Gonorrhea Cervicitis and Implications for Pregnancy Outcome. Are We Testing and Treating at the Right Time?”. J Reprod Med. 60 (7–8): 301–8. PMID 26380488.
  5. 5.0 5.1 Nugent RP, Hillier SL (1992). “Mucopurulent cervicitis as a predictor of chlamydial infection and adverse pregnancy outcome. The Investigators of the Johns Hopkins Study of Cervicitis and Adverse Pregnancy Outcome”. Sex Transm Dis. 19 (4): 198–202. PMID 1411834.
  6. 6.0 6.1 Chico RM, Mayaud P, Ariti C, Mabey D, Ronsmans C, Chandramohan D (2012). “Prevalence of malaria and sexually transmitted and reproductive tract infections in pregnancy in sub-Saharan Africa: a systematic review”. JAMA. 307 (19): 2079–86. doi:10.1001/jama.2012.3428. PMID 22665107.
  7. 7.0 7.1 Manhart LE, Jensen JS, Bradshaw CS, Golden MR, Martin DH (2015). “Efficacy of Antimicrobial Therapy for Mycoplasma genitalium Infections”. Clin Infect Dis. 61 Suppl 8: S802–17. doi:10.1093/cid/civ785. PMID 26602619.


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