Chagas disease classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

There is no established system for the classification of Chagas disease. We can classify Chagas disease based on the transmission route of Trypanosoma cruzi or based on the clinical manifestations (acute, chronic, congenital, cardiac, and digestive).

Classification

There is no established system for the classification of Chagas disease. However, we can classify Chagas disease based on the following: ^[1]

Based on the etiology transmission routes:
- Vector-borne transmission
- Congenital transmission
- Blood-borne transmission.
- Organ-derived transmission
- Oral transmission
Based on the clinical manifestations:
- Acute Chagas disease
- Chronic Chagas disease
- Congenital Chagas disease
- Indeterminate form of chronic T. cruzi infection
- Cardiac Chagas’ disease
- Digestive Chagas’ disease

References

↑ Bern C, Kjos S, Yabsley MJ, Montgomery SP (2011). “Trypanosoma cruzi and Chagas’ Disease in the United States”. Clin Microbiol Rev. 24 (4): 655–81. doi:10.1128/CMR.00005-11. PMC 3194829. PMID 21976603.

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[pmid21976603-1] Bern C, Kjos S, Yabsley MJ, Montgomery SP (2011). “Trypanosoma cruzi and Chagas’ Disease in the United States”. Clin Microbiol Rev. 24 (4): 655–81. doi:10.1128/CMR.00005-11. PMC 3194829. PMID 21976603.

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