Chichibabin pyridine synthesis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

The Chichibabin pyridine synthesis is a method for synthesizing pyridine rings. It was reported by Aleksei Chichibabin in 1924.

• A E Tschtschibabin (1924). “Über Kondensation der Aldehyde mit Ammoniak zu Pyridinebasen”. J. Prakt. Chem.: 122.
• M Weiss (1952). “Acetic Acid—Ammonium Acetate Reactions. An Improved Chichibabin Pyridine Synthesis”. Journal of the American Chemical Society. 74 (1): 200. doi:10.1021/ja01121a051.
• Robert L. Frank, Raymond P. Seven (1949). “Pyridines. IV. A Study of the Chichibabin Synthesis”. Journal of the American Chemical Society. 71 (8): 2629–2635. doi:10.1021/ja01176a008.

• http://drugfuture.com/OrganicNameReactions/onr72.htm

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