Choledocholithiasis laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Adenike Eketunde

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Overview

The laboratory data may be normal in as many as a thirds of patients with choledocholithiasis, and further evaluation of the Common bile duct is recommended by imaging studies to clarify the diagnosis.

Laboratory Findings

The laboratory data may be normal in as many as a third of patients with choledocholithiasis, and further evaluation of the Common bile duct is recommended by imaging studies to clarify the diagnosis.

Elevated serum bilirubin and alkaline phosphatase reflect biliary obstruction, but these are neither highly sensitive nor specific for CBD stones.
High Gamma-glutamyl transferase (GGT) level, greater than 90 U/L, has been suggested to be the most sensitive and specific indicator of CBD stones indicate a high risk of choledocholithiasis.^[1]

References

↑ Freitas ML, Bell RL, Duffy AJ (2006). “Choledocholithiasis: evolving standards for diagnosis and management”. World J Gastroenterol. 12 (20): 3162–7. doi:10.3748/wjg.v12.i20.3162. PMC 4087957. PMID 16718834.

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[pmid16718834-1] Freitas ML, Bell RL, Duffy AJ (2006). “Choledocholithiasis: evolving standards for diagnosis and management”. World J Gastroenterol. 12 (20): 3162–7. doi:10.3748/wjg.v12.i20.3162. PMC 4087957. PMID 16718834.

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