Chondrosarcoma risk factors
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]
Overview
Common risk factors in the development of chondrosarcoma are benign cartilage tumors such as enchondromas, osteochondromas, multiple exostoses, Ollier’s disease, and Maffucci’s syndrome.
Risk Factors
Chondrosarcoma may arise from pervious benign cartilage tumors. Some of these tumors are:[1][2][3][4]
- Enchondromas are type of benign bone tumor that often occurs in the hands, but can also occur in other sites of the body.
- Osteochondromas are benign tumors that arise near the growth plate of the bone.
- Multiple exostoses are multiple overgrowths of cartilage that occur at the end of the growth plate.
- Ollier’s disease is a disease causing multiple enchondromas.
- Maffucci’s syndrome is a disease with multiple enchondromas and angiomas.
References
- ↑ Altay M, Bayrakci K, Yildiz Y, Erekul S, Saglik Y (2007). “Secondary chondrosarcoma in cartilage bone tumors: report of 32 patients”. J Orthop Sci. 12 (5): 415–23. doi:10.1007/s00776-007-1152-z. PMID 17909925.
- ↑ Silve C, Jüppner H (2006). “Ollier disease”. Orphanet J Rare Dis. 1: 37. doi:10.1186/1750-1172-1-37. PMC 1592482. PMID 16995932.
- ↑ Mavrogenis AF, Gambarotti M, Angelini A, Palmerini E, Staals EL, Ruggieri P; et al. (2012). “Chondrosarcomas revisited”. Orthopedics. 35 (3): e379–90. doi:10.3928/01477447-20120222-30. PMID 22385450.
- ↑ Peabody, Terrance (2014). Orthopaedic oncology : primary and metastatic tumors of the skeletal system. Cham: Springer. ISBN 9783319073224.
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