Chronic lymphocytic leukemia MRI

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

MRI may be performed to detect spinal cord bone infiltration among chronic lymphocytic leukemia patients. MRI can also be used to assess for lymphadenopathy with a greater level of detail than physical examination alone.

• MRI may be performed to detect spinal cord bone infiltration among chronic lymphocytic leukemia patients.^[1]
• On spinal MRI, chronic lymphocytic leukemia is characterized by expansion of the spinal cord and lymph node enlargement.
• Spinal MRI image characteristics observed among chronic lymphocytic leukemia patients include:

• T1 weighted image demonstrates:

• Diffusely hypointense signal

• T1 weighted image with gadolinium contrast demonstrates:

• Heterogeneous enhancement

• T1 weighted image demonstrates:

• Heterogeneous and diffuse signal

• 
  Sagittal spinal T2 weighted MRI image illustrating heterogeneous and diffuse enhancement of chronic lymphocytic leukemia. ^[2]
• 
  Sagittal spinal T1 weighted MRI image illustrating hypointense diffuse signal of chronic lymphocytic leukemia. ^[2]

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