Churg-Strauss syndrome epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [3]

Overview

The incidence of eosinophilic granulomatosis with polyangiitis ranges from 2.5 to 16.6 per 100,000 individuals. Prevalence ranges from 2 to 16 per 100,000 individuals. Mean age at diagnosis is usually around 45-50 years. In general, eosinophilic granulomatosis with polyangiitis affects men and women equally.

The mean age at diagnosis of eosinophilic granulomatosis with polyangiitis is around 45-50 years.

In general, there is no gender predilection to eosinophilic granulomatosis with polyangiitis in western nations. In Japan, female predominance has been noted.^[3]

In general, there is no racial predominance to eosinophilic granulomatosis with polyangiitis.

↑ Martin RM, Wilton LV, Mann RD (May 1999). “Prevalence of Churg-Strauss syndrome, vasculitis, eosinophilia and associated conditions: retrospective analysis of 58 prescription-event monitoring cohort studies”. Pharmacoepidemiol Drug Saf. 8 (3): 179–89. doi:10.1002/(SICI)1099-1557(199905/06)8:3<179::AID-PDS414>3.0.CO;2-K. PMID 15073927.
↑ Loughlin JE, Cole JA, Rothman KJ, Johnson ES (March 2002). “Prevalence of serious eosinophilia and incidence of Churg-Strauss syndrome in a cohort of asthma patients”. Ann. Allergy Asthma Immunol. 88 (3): 319–25. doi:10.1016/S1081-1206(10)62015-7. PMID 11926627.
↑ Sada KE, Amano K, Uehara R, Yamamura M, Arimura Y, Nakamura Y, Makino H (July 2014). “A nationwide survey on the epidemiology and clinical features of eosinophilic granulomatosis with polyangiitis (Churg-Strauss) in Japan”. Mod Rheumatol. 24 (4): 640–4. doi:10.3109/14397595.2013.857582. PMID 24289197.