Cirrhosis screening

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sudarshana Datta, MD [2]

Overview

Screening for hepatocellular carcinoma (HCC) must be done in every cirrhotic patient. It is performed at a frequency of 6-12 months. Screening endoscopy for detection of esophageal varices must be performed at regular intervals in all patients.

Screening

Patients with cirrhosis must undergo screening for hepatocellular carcinoma (HCC) every 6-12 months.^[1]^[2]
Screening endoscopy for detection of esophageal varices must be performed:^[3]^[4]
- Within a year in case of compensated cirrhosis
- Within three months in case of complicated cirrhosis

References

↑ “Cirrhosis: Diagnosis, Management, and Prevention – American Family Physician”.
↑ Trevisani F, Santi V, Gramenzi A, Di Nolfo MA, Del Poggio P, Benvegnù L, Rapaccini G, Farinati F, Zoli M, Borzio F, Giannini EG, Caturelli E, Bernardi M (2007). “Surveillance for early diagnosis of hepatocellular carcinoma: is it effective in intermediate/advanced cirrhosis?”. Am. J. Gastroenterol. 102 (11): 2448–57, quiz 2458. doi:10.1111/j.1572-0241.2007.01395.x. PMID 17617210.
↑ Heidelbaugh JJ, Bruderly M (2006). “Cirrhosis and chronic liver failure: part I. Diagnosis and evaluation”. Am Fam Physician. 74 (5): 756–62. PMID 16970019.
↑ Qureshi W, Adler DG, Davila R, Egan J, Hirota W, Leighton J, Rajan E, Zuckerman MJ, Fanelli R, Wheeler-Harbaugh J, Baron TH, Faigel DO (2005). “ASGE Guideline: the role of endoscopy in the management of variceal hemorrhage, updated July 2005”. Gastrointest. Endosc. 62 (5): 651–5. doi:10.1016/j.gie.2005.07.031. PMID 16246673.

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[urlCirrhosis:_Diagnosis,_Management,_and_Prevention_-_American_Family_Physician-1] “Cirrhosis: Diagnosis, Management, and Prevention – American Family Physician”.

[pmid17617210-2] Trevisani F, Santi V, Gramenzi A, Di Nolfo MA, Del Poggio P, Benvegnù L, Rapaccini G, Farinati F, Zoli M, Borzio F, Giannini EG, Caturelli E, Bernardi M (2007). “Surveillance for early diagnosis of hepatocellular carcinoma: is it effective in intermediate/advanced cirrhosis?”. Am. J. Gastroenterol. 102 (11): 2448–57, quiz 2458. doi:10.1111/j.1572-0241.2007.01395.x. PMID 17617210.

[pmid16970019-3] Heidelbaugh JJ, Bruderly M (2006). “Cirrhosis and chronic liver failure: part I. Diagnosis and evaluation”. Am Fam Physician. 74 (5): 756–62. PMID 16970019.

[pmid16246673-4] Qureshi W, Adler DG, Davila R, Egan J, Hirota W, Leighton J, Rajan E, Zuckerman MJ, Fanelli R, Wheeler-Harbaugh J, Baron TH, Faigel DO (2005). “ASGE Guideline: the role of endoscopy in the management of variceal hemorrhage, updated July 2005”. Gastrointest. Endosc. 62 (5): 651–5. doi:10.1016/j.gie.2005.07.031. PMID 16246673.

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