Climazolam

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Climazolam^[1] (Ro21-3982) was introduced under licence as a veterinary medicine by the Swiss Pharmacutical company Gräub under the tradename ‘Climasol’.^[2] Climazolam is a benzodiazepine, specifically an imidazo benzodiazepine derivative developed by Hoffman-LaRoche. It is similar in structure to triazolam and is used in veterinary medicine for anesthetizing animals.^[3]^[4]

References

↑ US 4280957 – Imidazodiazepines and processes therefor
↑ http://www.drugs.com/international/climazolam.html
↑ Ganter M, Kanngiesser M (Aug 1991). “Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine”. Zentralbl Veterinarmed A (in German). 38 (7): 501–509. PMID 195024.
↑ Bettschart-Wolfensberger R, Taylor PM, Sear JW, Bloomfield MR, Rentsch K, Dawling S (Oct 1996). “Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam-ketamine combination in ponies premedicated with acepromazine and xylazine”. American Journal of Veterinary Research. 57 (10): 1472–1427. PMID 8896687.

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[1] US 4280957 – Imidazodiazepines and processes therefor

[2] ttp://www.drugs.com/international/climazolam.html

[3] Ganter M, Kanngiesser M (Aug 1991). “Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine”. Zentralbl Veterinarmed A (in German). 38 (7): 501–509. PMID 195024.

[4] Bettschart-Wolfensberger R, Taylor PM, Sear JW, Bloomfield MR, Rentsch K, Dawling S (Oct 1996). “Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam-ketamine combination in ponies premedicated with acepromazine and xylazine”. American Journal of Veterinary Research. 57 (10): 1472–1427. PMID 8896687.

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