Conserved domains

Conserved domains are recurring units in polypeptide chains (sequence and structure motifs), determined and classified by comparative analysis. Molecular evolution uses such domains as building blocks and these may be recombined in different arrangements to make different proteins with different functions. They might include a pattern of amino acids typical of a particular catalytic site, or perhaps the binding site for a regulator of a protein.

• Protein domains

• “What Is a Conserved Domain?” at the National Center for Biotechnology website

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