Cornea verticillata

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cornea verticillata: A bilateral, whorl-like corneal pattern of cream colored lines in a patient with Fabry disease.

Cornea verticillata, also called Fleischer vortex,^[1] Vortex keratopathy or Whorl keratopathy, is a condition characterised by corneal deposits at the level of the basal epithelium forming a faint golden-brown whorl pattern. It is seen in Fabry disease or in case of prolonged amiodarone intake.^[2]

Presentation

No ocular complaints or visual difficulty is usually present.^[2]^[3]

Pathophysiology

This keratopathy is probably a type of drug-induced lipidosis.^[2]

References

↑ “Definition: ‘Cornea Verticillata‘“. MediLexicon. Retrieved 29 November 2013.
↑ ^2.0 ^2.1 ^2.2 Chew, E; Ghosh, M; McCulloch, C (June 1982). “Amiodarone-induced cornea verticillata”. Canadian journal of ophthalmology. Journal canadien d’ophtalmologie. 17 (3): 96–9. PMID 7116220.
↑ Graff, Jordan M. (February 21, 2005). “Verticillata”. University of Iowa Health Care, Ophthalmology and Visual Sciences. Retrieved 29 November 2013.

[1] “Definition: ‘Cornea Verticillata‘“. MediLexicon. Retrieved 29 November 2013.

[pmid7116220-2] 2.0 ^2.1 ^2.2 Chew, E; Ghosh, M; McCulloch, C (June 1982). “Amiodarone-induced cornea verticillata”. Canadian journal of ophthalmology. Journal canadien d’ophtalmologie. 17 (3): 96–9. PMID 7116220.

[3] Graff, Jordan M. (February 21, 2005). “Verticillata”. University of Iowa Health Care, Ophthalmology and Visual Sciences. Retrieved 29 November 2013.

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