Crazy paving sign

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Crazy-paving sign is classically associated with pulmonary alveolar proteinosis. The linear network or reticular pattern in the crazy-paving sign is believed to result from a thickening of the interlobular septa, while areas of ground-glass opacity result from partial alveolar filling processes.

• Pulmonary alveolar proteinosis
• Pneumocystis carinii pneumonia
• Mucinous bronchoalveolar carcinoma
• Sarcoidosis
• Lipoid pneumonia
• Adult respiratory distress syndrome
• Pulmonary hemorrhage

On imaging, the sign appears as a linear network or reticular pattern with areas of ground-glass opacification.

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