Cretinism classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Cretinism may be classified into two groups which include transient and permanent cretinism. Permanent cretinism may classified into two subgroups including primary and secondary cretinism.

Classification

Cretinism may be classified based on the duration of thyroid hormones deficiency into two groups:^[1]
- Transient cretinism: Transient deficiency of the thyroid hormones which may be discovered at birth. Thyroid hormone levels returns back to normal after a period of time.
- Permanent cretinism: Permanent deficiency of the thyroid hormones which requires life long hormonal replacement. Permanent cretinism can be classified into two subgroups based on the location of the etiology:
  - Primary permanent cretinism
  - Secondary (central) permanent cretinism

References

↑ Rastogi MV, LaFranchi SH (2010). “Congenital hypothyroidism”. Orphanet J Rare Dis. 5: 17. doi:10.1186/1750-1172-5-17. PMC 2903524. PMID 20537182.

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[pmid20537182-1] Rastogi MV, LaFranchi SH (2010). “Congenital hypothyroidism”. Orphanet J Rare Dis. 5: 17. doi:10.1186/1750-1172-5-17. PMC 2903524. PMID 20537182.

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