Creutzfeldt-Jakob disease laboratory findings
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Routine laboratory tests are usually normal in Creutzfeldt Jakob disease. Analysis of CSF for 14-3-3 protein may be helpful in the diagnosis of Creutzfeldt-Jakob disease. Other elevated proteins in CSF may include S-100, neuron specific enolase, and Tau protein.
Laboratory Tests
- Routine laboratory tests are usually normal in Creutzfeldt Jakob disease.[1]
- Liver function tests may occasionally be elevated.[2]
- In CSF, elevated concentrations of following protein markers may be remarkable in Creutzfeldt-Jakob disease:[3]
- 14-3-3 protein
- S-100
- Neuron specific enolase
- Tau protein
References
- ↑ “[History of the Department of Physiology, School of Medicine, Nagoya University]”. Nihon Seirigaku Zasshi (in Japanese). 29 (4): 187–96. 1967. PMID 4863517.
- ↑ Tanaka, M.; Iizuka, O.; Yuasa, T. (1992). “Hepatic dysfunction in Creutzfeldt-Jakob disease”. Neurology. 42 (6): 1249. PMID 1302460. Unknown parameter
|month=ignored (help) - ↑ Sanchez-Juan, P.; Green, A.; Ladogana, A.; Cuadrado-Corrales, N.; Sáanchez-Valle, R.; Mitrováa, E.; Stoeck, K.; Sklaviadis, T.; Kulczycki, J. (2006). “CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease”. Neurology. 67 (4): 637–43. doi:10.1212/01.wnl.0000230159.67128.00. PMID 16924018. Unknown parameter
|month=ignored (help)
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