Creutzfeldt-Jakob disease risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Risk factors for Creutzfeldt-Jakob disease include advanced age, positive family history, personal history of psychosis, history of surgical procedures, grafts or implants, and history of ingestion of human growth hormones or contaminated meat.

Risk factors for Creutzfeldt Jakob disease include the following:

Advanced age
Family history of Creutzfeldt-Jakob disease^[1]
Personal history of psychosis^[1]
Multiple surgical or graft procedures, such as electrode implantation, corneal grafting, or dura mater grafting^[2]
Living on a farm for more than 10 yrs^[2]
People receiving human growth hormone (HGH)
Consumption of contaminated beef (associated with increased risk of variant Creutzfeldt-Jakob disease)^[3]

↑ ^1.0 ^1.1 Wientjens, DP.; Davanipour, Z.; Hofman, A.; Kondo, K.; Matthews, WB.; Will, RG.; van Duijn, CM. (1996). “Risk factors for Creutzfeldt-Jakob disease: a reanalysis of case-control studies”. Neurology. 46 (5): 1287–91. PMID 8628468. Unknown parameter |month= ignored (help)
↑ ^2.0 ^2.1 Collins, S.; Law, MG.; Fletcher, A.; Boyd, A.; Kaldor, J.; Masters, CL. (1999). “Surgical treatment and risk of sporadic Creutzfeldt-Jakob disease: a case-control study”. Lancet. 353 (9154): 693–7. PMID 10073510. Unknown parameter |month= ignored (help)
↑ Ward, HJ.; Everington, D.; Cousens, SN.; Smith-Bathgate, B.; Leitch, M.; Cooper, S.; Heath, C.; Knight, RS.; Smith, PG. (2006). “Risk factors for variant Creutzfeldt-Jakob disease: a case-control study”. Ann Neurol. 59 (1): 111–20. doi:10.1002/ana.20708. PMID 16287153. Unknown parameter |month= ignored (help)