Cryoglobulinemia historical perspective
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Feham Tariq, MD [2]
Overview
In 1966, Meltzer and Franklin were the first ones to describe Meltzer triad which includes following clinical manifestations, purpura, arthralgia, and weakness.
Historical Perspective
The historical perspective of cryoglobulinemia is as follows:[1][2]
- In 1966, Meltzer and Franklin were the first ones to describe Meltzer triad which includes following clinical manifestations, purpura, arthralgia, and weakness.
- This triad of clinical manifestations was seen in the patients having essential mixed cryoglobulinemia.
References
- ↑ Meltzer M, Franklin EC, Elias K, McCluskey RT, Cooper N (1966). “Cryoglobulinemia–a clinical and laboratory study. II. Cryoglobulins with rheumatoid factor activity”. Am J Med. 40 (6): 837–56. PMID 4956871.
- ↑ Monti G, Galli M, Invernizzi F, Pioltelli P, Saccardo F, Monteverde A; et al. (1995). “Cryoglobulinaemias: a multi-centre study of the early clinical and laboratory manifestations of primary and secondary disease. GISC. Italian Group for the Study of Cryoglobulinaemias”. QJM. 88 (2): 115–26. PMID 7704562.
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