Cys-loop receptors

The Cys-loop ligand-gated ion channel superfamily is comprised of nicotinic acetylcholine, GABA_A, GABA_C, glycine and 5-HT₃ receptors that are composed of five protein subunits and possess a characteristic loop formed by a disulphide bond between two cysteine residues.

• Sine S, Engel A (2006). “Recent advances in Cys-loop receptor structure and function”. Nature. 440 (7083): 448–55. PMID 16554804.

• Overview at gwumc.edu

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