DRESS syndrome secondary prevention

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Serge Korjian M.D.

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Overview

Secondary preventive measures to avoid DRESS syndrome include avoidance of drug re-exposure, screening for cross-reacting agents using in vitro lymphocyte toxicity assays, and possibly desensitization techniques.

Secondary Prevention

Secondary preventive measures to avoid DRESS syndrome include the following:^[1]

Avoid re-exposure to drugs that have previously caused DRESS syndrome
Screen for cross-reacting agents using in vitro lymphocyte toxicity assays
Desensitization has not been reported to be effective in some case reports, but the true effectiveness of the desensitization has not been studied.^[2]

References

↑ Tas S, Simonart T (2003). “Management of drug rash with eosinophilia and systemic symptoms (DRESS syndrome): an update”. Dermatology. 206 (4): 353–6. doi:69956 Check |doi= value (help). PMID 12771485.
↑ Moreno-Ancillo A, López-Serrano MC (1998). “Hypersensitivity reactions to drugs in HIV-infected patients. Allergic evaluation and desensitization”. Clin Exp Allergy. 28 Suppl 4: 57–60. PMID 9761034.

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[pmid12771485-1] Tas S, Simonart T (2003). “Management of drug rash with eosinophilia and systemic symptoms (DRESS syndrome): an update”. Dermatology. 206 (4): 353–6. doi:69956 Check |doi= value (help). PMID 12771485.

[pmid9761034-2] Moreno-Ancillo A, López-Serrano MC (1998). “Hypersensitivity reactions to drugs in HIV-infected patients. Allergic evaluation and desensitization”. Clin Exp Allergy. 28 Suppl 4: 57–60. PMID 9761034.

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